Pediatrics and Neonatology

Biography:

Will Update Soon...

Abstract:

For a long time, it was believed that children are resistant to pain, and the benefits of the treatment is much more important than the emotional reaction of the child.   During the stay in the maternity hospital, and even more so in the hospital, full-term and especially premature newborns endure a large number of manipulations and procedures, most of which are quite painful. Adequate analgesia and pain prevention in manipulations and procedures can reduce discomfort of the child, minimize hormonal and metabolic changes in response to stress, improve the tolerance of medical procedures and care procedures. 

The aim of this study was to study non-drug methods of anesthesia in the performance of various painful manipulations in the neonatal Department: vaccination against hepatitis B and BCG, intramuscular administration of sodium Menadione, neonatal screening.

The analysis of several non-drug methods of anesthesia in the performance of painful manipulations in the neonatal Department. The most effective and safe method of anesthesia was breastfeeding during painful manipulations. Taking into account the results obtained in our maternity hospital, it was decided to perform all the painful manipulations in newborns on the breast of the mother.

Biography:

She is a researcher in ST. LUKE’S MEDICAL CENTER- GLOBAL CITY INSTITUTE OF PEDIATRICS AND CHILD HEALTH

Abstract:

Achalasia is a rare disorder, particularly in Pediatrics, characterized by esophageal aperistalsis and inadequate relaxation of the lower esophageal sphincter. Its etiology remains unclear and is mostly idiopathic. This is a case of an adolescent male who presented with progressive dysphagia, occasional chest pain, and significant weight loss, and was diagnosed with Esophageal Achalasia through upper GI series, endoscopy, and manometry. The patient underwent Heller’s Myotomy, the surgical gold standard for treatment.

Biography:

CellSonic, having set it up with his own capital earned from property development and telecommunications. He has no debts and cannot be pushed around. He brings a new perspective to medicine.

Modern doctors are only taught about biochemistry which has only three products: vaccines, anti-biotics and anaesthetics. They only serve acute conditions. Everything else produced by Big Pharma does not work. Professor Hague’s discoveries have pioneered biophysics which is the key to chronic diseases including cancer. Moreover, the role of the mind is central and this cannot be managed with drugs or a machine. Where Big Pharma fails, CellSonic succeeds.

His company has two websites:

CellSonic Medical (cellsonic-medical.com)

CellSonic Beauty (cellsonic-beauty.com)

Of interest is Sapiens Shield sapiensshield.com with four short, old videos. The electrical properties of cells have been known since before drugs were made in factories.

Professor Hague’s lecture goes beyond paediatrics and will educate everyone who wants to heal. He will take questions but be sure you have first read everything on his websites. This is a new branch of medicine and you have a lot to learn. There are no side effects.

Abstract:

Late last year, Professor Andrew Hague was asked to help a man whose tongue had been cut in half to remove cancer. There was much correspondence revealing a lot about the man and his parents. The Professor realised that the conditions for cancer occurred before birth. To understand how the cure was done, there are two parts to cancer: the body and the mind.

Modern medicine uses only biochemistry and as cancer is an electrical fault it is unable to cure cancer. Biophysics are needed, a subject not taught to doctors. They know how to administer drugs and cut open patients but for chronic disease, including cancer, they are helpless.

Professor Hague’s lecture will give you all the answers and leave you wanting to ask more questions. The problems you see with children cannot be resolved without helping the parents and problems in adults cannot be solved without understanding their childhood.

Biography:

Will update soon..

Abstract:

Aim of the work: It was to estimate the carotid intima-media thickness (CIMT), lipid profifile, serum amyloid A and vitamin D in Familial MediterraneanFever(FMF) patients and to explore the relationship between CIMT and FMF. Patients and methods: The study comprised forty-fifive FMF patients diagnosedduring the attack free period and 40 healthy children with similar demographicfeatures as control. The diagnosis of the FMF cases was confirmed byclinical, laboratory assessments and confirmed by the molecular diagnosis.

The CIMT, lipid profile, complete blood picture, serum amyloid A(SAA) levels, vitamin D and the growth pattern were investigated. Results: The study showed no significant difference of CIMT among patientsandcontrols, significant decrease of vitamin D levels, while lipid profile parameters, triglyceride (TG)toHDL-Cholesterol (HDLC) ratio, serum amyloid A were significantly increased. Asignificant correlation was present between the CIMT with the serumcholesterol, low density lipoprotein and triglycerides as well as between SAAand thenumberof attacks. In addition, vitamin D levels showed significant negative correlationwith colchicine. M694I mutation was the most prevalent among FMFpatients. Growth parameters were normal in FMF cases. Conclusion: This study sheds light that the normal CIMT in the FMFpatientsmakes it difficult to describe the children as having subclinical atherosclerosisalthough the higher TG/HDL ratio reflects their risk of atherosclerosis. Moreover, significant decrease of vitamin D in FMF patients was observed. Thegrowthparameters of the FMF patients on regular treatment of colchicine werenotaffected.

Biography:

Magarsa Lami is  a professor in Haramaya University, College of Medicine and Health Sciences, Department of Nursing and Midwifery, Harar, Ethiopia.

Abstract:

Background: Birth asphyxia is a serious clinical problem of the newborn babies, which occurs due to impaired blood-gas exchange and results in hypoxemia. Despite improvements in the diagnosis and management of perinatal asphyxia, it has become the leading cause of admission and neonatal mortality, especially in developing countries.

Objective: The aim of this study was to assess factors associated with perinatal asphyxia among live births in the public health facilities of Bahir Dar city, Northwest Ethiopia, 2021.

Method: Health facility based cross-sectional study was employed from April 1-30/2021 in the public health facilities of Bahir Dar city among 517 mothers-newborn pairs. The data were collected by systematic random sampling technique, entered by using Epi data 3.1 and analyzed using SPSS 25.0 version. Bivariate and multivariate logistic regression analyses was employed to estimate the crude and adjusted odds ratio with a confidence interval of 95% and a P-value of less than 0.05 considered statistically significant. Frequency tables, figures and descriptive summaries were used to describe the study variables.

Result: In this study, 21.7% (95% CI: 18.2% – 25.5%) of the newborns had perinatal asphyxia. Mal-presentation [AOR=4.06, 95% CI= 2.08-7.94], uterotonics drug administration [AOR= 2.78, 95% CI=1.67- 4.62], meconium-stained amniotic fluid [AOR=4.55, 95% CI=2.66, 7.80], night time delivery [AOR=1.91, 95% CI=1.17, 3.13] and preterm delivery [AOR=3.96, 95% CI=1.98, 7.89] were significantly associated with perinatal asphyxia.

Conclusion and Recommendation: In the present study, the proportion of perinatal asphyxia was high. Fetal mal-presentation, uterotonics drug administrations, meconium-stained amniotic fluid, delivery at night time, and preterm delivery were significantly associated with perinatal asphyxia. To mitigate this problem, there is a need to focus on early identification of the risk factors like fetal mal-presentation, preterm labor/delivery, and managing them appropriately. Administering of uterotonics drugs should be based on indication with close supervision.

Keywords: Asphyxia; Bahir Dar University; Determinant factors; Ethiopia; Perinatal.

Biography:

MBBS degree from Omdurman Islamic university, Sudan Registrar of pediatrics at Sudan medical specialization board (S.M.S.B) Research collaborator at Larkin community hospital division of clinical and transitional research, south Miami, Florida, USA.

Abstract:

Cystic fibrosis (CF) is an inherited autosomal recessive disorder caused by genetic mutations in CFTR protein. The FDA approved various CF gene modulators, the most recent was the nextgeneration gene therapy in 2019. This paper aimed at the efficacy of the first triple gene therapy in children and adolescents suffering from cystic fibrosis. A systematic review and metanalysis was conducted following PRISMA guidelines through PubMed/Medline, Clinical trials.gov, Google Scholar, Scopus, Embase, and Europe PMC using the keywords: “Ivacaftor,” “Elexacaftor,” “Tezacaftor,” VX_661”, VX_770”, “VX_445”, “cystic fibrosis” and “gene therapy.” A total of ten randomized clinical trials were included for analysis. Significant absolute change was demonstrated from baseline through 4 weeks favors toward the triple CF gene potentiators in predictive FEV1 [MD=11.80,95%CI=8.47_15.12, p value=<0.00001]; as well as CF_QR score [MD=16.90,95%CI=12.73_21.06, p value=<0.00001] , and BMI kg/m² change [MD=1.04,95%CI=0.84_1.24, p value=<0.00001]. On the same hand, non-significant change was noticed for chloride ion channels activity in treatment group when compared to placebo or VX_770/VX_661 [MD= -12.57,95%CI=-94.46_69.32, p value=0.76]. For Ivacaftor therapy, only a significant reduction in sweat chloride test value toward the treatment group was observed by Ramsey et al., Davies et al., and Moss et al. through 24 weeks [MD=-35.89,95%CI=-59.31_-12.47, p value=0.003]. Tez/Iva group showed no difference between treatment and placebo in term of p FEV1 [MD=1.72,95%CI=-0.95_4.39, p value=0.21]; sweat chloride test [MD=-4.33,95%CI=- 10.43_1.78, p value=0.16]; respiratory domain score [MD=1.82,95%CI=0.92_4.56, p value=0.19]; and a non-notifiable BMI change from baseline [MD=0.03,95%CI=-0.09_0.14, p value=0.66]. In children aged ≥ 6 y old and adolescents with F508del_CFTR mutation, Elexacaftor–Tezacaftor–Ivacaftor tend to be more effective than first-generation therapy, which showed promising results by improving the lung function, body weight, and respiratory-related quality of life.

Biography:

Jane Koech has her expertise in monitoring and evaluation and passion in improving maternal newborn and child outcome. . She has built this after years of experience in research, evaluation, and program based implementation. She has also strong background in community dynamics and engagement using ecological model. 

Abstract:

Nairobi City County, with its major, informal urban settlements, is home to a large and growing proportion of people living with HIV. Alike in other cities, urban dynamics – such as high mobility, high population density and high concentrations of marginalized, fragile and stigmatized communities – create and exacerbate vulnerability to HIV infection (The Nairobi City County HIV Fast Track Report 2015).he youth. Nairobi City County Health Management team, is working to eliminate mother-to-child transmission (MTCT) in Nairobi’s informal settlements.  In 2016, the Kariobangi Health Center (HC), located in Kasarani Sub-county, recorded a high early infant diagnosis (EID) positivity rate of 6.1% (NASCOP EID 2015 .hence comprehensive strategy to reduce MTCT was necessary. The objective of the study was to establish the most effective interventions in eliminating mother to child transmission (MTCT) in Kariobangi H/C through comprehensive Provision of comprehensive eMTCT services.

Methodology

From October 2016 to March 2017, a strategy to improve delivery of prevention of MTCT (PMTCT) services was implemented. HTS counselors performed HIV testing at first antenatal care (ANC), labor and delivery, and six-week postpartum visits to ensure timely initiation of ART and follow-up.  Mentor Mothers conducted aggressive follow-up with clients who declined ART, Continuous medical education and on-the-job training were done to capacitate nurses to provide PMTCT care, Monthly Work Improvement Team (WIT) meetings were held to review the PMTCT continuum of care and   Peer education and psychosocial support

Results

Timely ART initiation for PMTCT clients has led to high ART uptake in Kariobangi HC. Rates of ART provision were sustained with 100% (110) of HIV-infected pregnant women provided with ART in 2016 and 100% (93) in 2017.and the interventions have also led to a reduction in HIV positivity for infants under the age of 12 months from 6.1% in 2016 to 2.4% in 2018 %.

Conclusion

Provision of comprehensive PMTCT services, timely ART initiation, and continuous follow up of the mother-baby pair are key in reducing pediatric HIV infections and ultimately preventing child deaths.